ALLELE SPECIFIC PATTERNS OF SUPPRESSION OF THE VERMILION LOCUS IN DROSOPHILA MELANOGASTER
نویسندگان
چکیده
منابع مشابه
Molecular variation at the vermilion locus in geographically diverse populations of Drosophila melanogaster and D. simulans.
We surveyed nucleotide variation at vermilion in population samples of Drosophila melanogaster from Africa, Asia and the Americas to test the hypothesis that the vermilion gene was a target of balancing selection and to improve our understanding of geographic differentiation. Patterns of polymorphism and divergence showed no evidence for non-neutral evolution. However, the frequency spectrum of...
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Mutations in the Punch locus result in loss of GTP cyclohydrolase activity, but all mutations do not affect the enzyme in the same way. There are at least three classes of Punch mutations. One class results in a dominant eye color, recessive lethal phenotype. A second class of mutations also causes a recessive lethal phenotype, but heterozygous mutants have normal eye color. They show loss of G...
متن کاملEnzymatic studies with the suppressor of vermilion of Drosophila melanogaster.
UPPRESSION is the complete or partial restoration of the wild-type phenotype by one gene in the presence of another nonallelic mutant gene that alone causes a mutant phenotype. Intragenic “suppressors” have also been reported (CRICK, BARNETT, BRENNER and WATTS-TOBIN 1961; HELINSKI and YANOFSKY 1963) but the term “second site reversion” used by HELINSKI and YANOFSKY seems useful in distinguishin...
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I N a previous paper (LIFSCHYTZ and FALK 1969b) we showed that by using the specific interaction pn-K-pn (prune--Killer-prune) we could construct an efficient screening system in which the products of reversions in the p n and K-pn loci were the only viable male-progeny. The few female progeny that survived served for estimating the number of tested zygotes. K p n is a dominant mutant, interact...
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ژورنال
عنوان ژورنال: Genetics
سال: 1968
ISSN: 1943-2631
DOI: 10.1093/genetics/59.4.477